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Article

Defective Lysosomal Lipid Catabolism as a Common Pathogenic Mechanism for Dementia.

Neuromolecular medicine - 1 Mar 2021

Lee Jun Yup, Marian Oana C, Don Anthony S

Abstract excerpt

Dementia poses an ever-growing burden to health care and social services as life expectancies have grown across the world and populations age. The most common forms of dementia are Alzheimer's disease (AD), vascular dementia, frontotemporal dementia (FTD), and Lewy body dementia, which includes Parkinson's disease (PD) dementia and dementia with Lewy bodies (DLB). Genomic studies over the past 3 decades have...

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PMID: 33550528
DOI: 10.1007/s12017-021-08644-4

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