Article

Circulating mitochondrial bioenergetics as fingerprint of the hepatic one: how to monitor genetic MASLD

2024-05-09

Abstract excerpt

<h4>Background & Aims</h4> Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) pathogenesis is shaped by genetics and mitochondrial dysfunction. Recently, we demonstrated that the co-presence of patatin- like phospholipase domain-containing 3 ( PNPLA3 ), transmembrane 6 superfamily member 2 ( TM6SF2 ) and membrane bound o-acyltransferase domain-containing 7 ( MBOAT7 ) polymorphisms predisposes to...

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Literature Corpus work: 8290b5f0-0c96-54ac-af88-1f768d621cd1
DOI: 10.1101/2024.05.06.592717

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