Article

Remodeling of Mitochondrial Plasticity: The Key Switch from NAFLD/NASH to HCC

2021-03-30

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and the third-leading cause of cancer-related mortality. Currently, the global burden of nonalcoholic fatty liver disease (NAFLD) has dramatically overcome both viral and alcohol hepatitis thus becoming the main cause of HCC incidence. NAFLD pathogenesis is severely influenced by lifestyle and genetic predisposition. Mitochondria are...

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Literature Corpus work: 72b929ec-7143-55a8-920f-9f76872aada9
DOI: 10.20944/preprints202103.0714.v1

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