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Article

Interplay between MicroRNAs and Oxidative Stress in Neurodegenerative Diseases

30 Nov 2019

Abstract excerpt

MicroRNAs are post-transcriptional regulators of gene expression, crucial for neuronal differentiation, survival, and activity. Age-related dysregulation of microRNA biogenesis increases neuronal vulnerability to cellular stress and may contribute to the development and progression of neurodegenerative diseases. All major neurodegenerative disorders are also associated with oxidative stress, which is widely...

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PMID: 31801298
DOI: 10.3390/ijms20236055

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