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Sestrins at the Interface of ROS Control and Autophagy Regulation in Health and Disease

7 May 2019

Abstract excerpt

Reactive oxygen species (ROS) and autophagy are two highly complex and interrelated components of cell physiopathology, but our understanding of their integration and their contribution to cell homeostasis and disease is still limited. Sestrins (SESNs) belong to a family of highly conserved stress-inducible proteins that orchestrate antioxidant and autophagy-regulating functions protecting cells from various...

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PMID: 31205582
DOI: 10.1155/2019/1283075

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