Article

Ladostigil attenuates the oxidative and ER stress in human neuroblast-like SH-SY5Y cells

2021-08-08

Abstract excerpt

A hallmark of the aging brain is the robust inflammation mediated by microglial activation. Neuroinflammation resulting from the induction of oxidative stress in neurodegenerative diseases and following brain injury. Chronic treatment of aging rats by ladostigil, a compound with antioxidant and anti-inflammatory function, prevented microglial activation and learning deficits. In this study, we investigate the effe...

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Literature Corpus work: 8fbdab37-461d-556e-9df4-7eb510961388
DOI: 10.1101/2021.08.07.455498

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