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Histopathology-inferred spatial transcriptomics characterizes the tumor microenvironment in 1,500 head and neck tumors and predicts clinical outcomes

2026-05-19

Abstract excerpt

Head and neck squamous cell carcinoma (HNSC) is a prevalent malignancy associated with poor prognosis despite recent therapeutic advances. We hypothesized that a comprehensive understanding of the spatial heterogeneity and organization of the tumor microenvironment (TME) can substantially improve risk stratification and prediction of treatment response in HNSC. As spatial transcriptomics (ST) remains labor-intensi...

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Literature Corpus work
8274c205-417d-5e00-8aa8-4a7b341b8782
DOI
10.64898/2026.05.16.725687
Open publication

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Histopathology-inferred spatial transcriptomics characterizes the tumor microenvironment in 1,500 head and neck tumors and predicts clinical outcomesDOI 10.64898/2026.05.16.725687
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