Article
Use of a natural hybrid zone for genomewide association mapping of craniofacial traits in the house mouse.
Molecular ecology - 1 Dec 2014
Pallares Luisa F, Harr Bettina, Turner Leslie M, Tautz Diethard
Abstract excerpt
The identification of the genes involved in morphological variation in nature is still a major challenge. Here, we explore a new approach: we combine 178 samples from a natural hybrid zone between two subspecies of the house mouse (Mus musculus domesticus and Mus musculus musculus), and high coverage of the genome (~ 145K SNPs) to identify loci underlying craniofacial shape variation. Due to the long history of...
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