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Article

Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination.

PLoS genetics - 1 Nov 2015

Pallares Luisa F, Carbonetto Peter, Gopalakrishnan Shyam, Parker Clarissa C, Ackert-Bicknell Cheryl L, Palmer Abraham A, Tautz Diethard

Abstract excerpt

The vertebrate cranium is a prime example of the high evolvability of complex traits. While evidence of genes and developmental pathways underlying craniofacial shape determination is accumulating, we are still far from understanding how such variation at the genetic level is translated into craniofacial shape variation. Here we used 3D geometric morphometrics to map genes involved in shape determination in a...

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PMID: 26523602
DOI: 10.1371/journal.pgen.1005607
PMCID: PMC4629907

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Source receipt: pubmed, retrieved 7 Sept 2026.

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