Article

The molecular basis for prognosis of isoniazid resistance in<i>Mycobacterium tuberculosis</i>

2024-09-23

Abstract excerpt

Tuberculosis (TB), a disease that kills 1.5 million people every year, is a major global public health concern. The emergence of drug resistance in M. tuberculosis , the obligate pathogen of TB is a major challenge. The emergence of resistance seems to follow an order that might be exploited for novel therapeutic strategies. In most cases resistance to isoniazid (INH) emerges first, followed by rifampicin, then ei...

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Literature Corpus work: 81f1b1fa-ff80-5e88-a2c6-7f54031ea178
DOI: 10.1101/2024.09.21.24314105

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