Article

Comprehensive mapping of tissue cell architecture via integrated single cell and spatial transcriptomics

2020-11-17

Abstract excerpt

The spatial organization of cell types in tissues fundamentally shapes cellular interactions and function, but the high-throughput spatial mapping of complex tissues remains a challenge. We present сell2location, a principled and versatile Bayesian model that integrates single-cell and spatial transcriptomics to map cell types in situ in a comprehensive manner. We show that сell2location outperforms existing tool...

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Literature Corpus work: 81bdaecd-7602-5f66-9151-4510990e7d80
DOI: 10.1101/2020.11.15.378125

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