Article

Frequently Together, Among Model Systems Molecular Alterations: Cancer Maintenance Markers with Translational Study Design

2024-01-30

Abstract excerpt

In contrast to cancer driver gene alterations, genes with alterations occurring frequently together are unlikely to play a direct role in tumor development, and more likely to contribute to normal cellular functions necessary for the ongoing maintenance and survival of the tumor, with the most robust of these genes preserved across model systems. We introduce two molecular signature-centric methods, RECO (recurrin...

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Literature Corpus work: 81aab96b-2083-530e-9136-9708d4ce1f4c
DOI: 10.1101/2024.01.26.577415

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