Article

MechanoAge, a machine learning platform to identify individuals susceptible to breast cancer based on mechanical properties of single cells

2025-08-12

Abstract excerpt

<h4>Background</h4> Existing breast cancer risk models inadequately identify individuals at latent risk, particularly among women without known genetic mutations or family history. Risk is often underestimated or overestimated due to reliance on population-level data and neglect of cellular aging and mechanobiological alterations. <h4>Methods</h4> We profiled primary human mammary epithelial cells (HMECs) from w...

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Literature Corpus work: 818f8e20-5fc4-5fc3-8f99-5928a725b772
DOI: 10.1101/2025.08.08.668946

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