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Article

Single cell imaging-based chromatin biomarkers for tumor progression.

Scientific reports - 29 Nov 2021

Venkatachalapathy Saradha, Jokhun Doorgesh S, Andhari Madhavi, Shivashankar G V

Abstract excerpt

Tumour progression within the tissue microenvironment is accompanied by complex biomechanical alterations of the extracellular environment. While histopathology images provide robust biochemical markers for tumor progression in clinical settings, a quantitative single cell score using nuclear morphology and chromatin organization integrated with the long range mechanical coupling within the tumor microenvironment...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 34845273
DOI: 10.1038/s41598-021-02441-6
PMCID: PMC8630115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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