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Article

Photochemical pre-bleaching of formalin-fixed archival prostate tissues significantly reduces autofluorescence to facilitate multiplex immunofluorescence staining

2021-11-11

Abstract excerpt

The characterization of tissues using multiple different primary antibodies detected by secondary antibodies, each possessing a different colored fluorophore (multiplex immunofluorescence), is a powerful technique but often impaired by endogenous autofluorescence present in the specimen. Our current research involves the use of multiplex immunofluorescence to identify specific cell phenotypes within the tumor micr...

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Literature Corpus work
81744c3c-0abb-51ab-a52f-ced55f4dd902
DOI
10.1101/2021.11.09.467916
Open publication

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Photochemical pre-bleaching of formalin-fixed archival prostate tissues significantly reduces autofluorescence to facilitate multiplex immunofluorescence stainingDOI 10.1101/2021.11.09.467916
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