Article

Analysis of Amino Acid Variants in Malignant Melanoma Cells Resistant to BRAF inhibition

2020-12-15

Abstract excerpt

Analysis of patient-specific nucleotide variants is a cornerstone of personalised medicine. Although only 2% of the genomic sequence is protein-coding, mutations occurring in these regions have the potential to influence protein structure and may have severe impact on disease aetiology. Of special importance are variants that affect modifiable amino acid residues, as protein modifications involved in signal transd...

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Literature Corpus work: 8132d618-0225-588b-8edd-813c685f8844
DOI: 10.1101/2020.12.15.422879

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