Article
The Human Melanoma Proteome Atlas-Complementing the melanoma transcriptome.
Clinical and translational medicine - 1 Jul 2021
Betancourt Lazaro Hiram, Gil Jeovanis, Sanchez Aniel, Doma Viktória, Kuras Magdalena, Murillo Jimmy Rodriguez, Velasquez Erika, Çakır Uğur, Kim Yonghyo, Sugihara Yutaka, Parada Indira Pla, Szeitz Beáta, Appelqvist Roger, Wieslander Elisabet, Welinder Charlotte, de Almeida Natália Pinto, Woldmar Nicole, Marko-Varga Matilda, Eriksson Jonatan, Pawłowski Krzysztof, Baldetorp Bo, Ingvar Christian, Olsson Håkan, Lundgren Lotta, Lindberg Henrik, Oskolas Henriett, Lee Boram, Berge Ethan, Sjögren Marie, Eriksson Carina, Kim Dasol, Kwon Ho Jeong, Knudsen Beatrice, Rezeli Melinda, Malm Johan, Hong Runyu, Horvath Peter, Szász A Marcell, Tímár József, Kárpáti Sarolta, Horvatovich Peter, Miliotis Tasso, Nishimura Toshihide, Kato Harubumi, Steinfelder Erik, Oppermann Madalina, Miller Ken, Florindi Francesco, Zhou Quimin, Domont Gilberto B, Pizzatti Luciana, Nogueira Fábio C S, Szadai Leticia, Németh István Balázs, Ekedahl Henrik, Fenyö David, Marko-Varga György
Abstract excerpt
The MM500 meta-study aims to establish a knowledge basis of the tumor proteome to serve as a complement to genome and transcriptome studies. Somatic mutations and their effect on the transcriptome have been extensively characterized in melanoma. However, the effects of these genetic changes on the proteomic landscape and the impact on cellular processes in melanoma remain poorly understood. In this study, the...
Read the complete abstract on PubMed