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Article

The next generation of metastatic melanoma: uncovering the genetic variants for anti-BRAF therapy response.

Oncotarget - 3 May 2016

Pinto Rosamaria, De Summa Simona, Strippoli Sabino, Pilato Brunella, Azzariti Amalia, Guida Gabriella, Guida Michele, Tommasi Stefania

Abstract excerpt

Metastatic melanoma (MM) is a highly aggressive cancer with a median overall survival of 6-9 months, notwithstanding the numerous efforts in development of new therapeutic approaches. To this aim we tested the clinical applicability of the Ion Torrent Personal Genome Machine to simultaneously screen MM patients in order to individuate new or already known SNPs and mutations able to predict the duration of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26863566
DOI: 10.18632/oncotarget.7175
PMCID: PMC5041894

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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