Article

Mitochondrial Structure and Polarity in Dendrites and the Axon Initial Segment are Regulated by Homeostatic Plasticity and Dysregulated in Fragile X Syndrome

2021-02-02

Abstract excerpt

<title>Abstract</title> <p>Mitochondrial dysfunction has long been overlooked in neurodevelopmental disorders, but recent studies have provided new links to genetic forms of autism, including Rett syndrome and Fragile X Syndrome (FXS). In parallel, recent studies have uncovered important basic functions of mitochondria to power protein synthesis, synaptic plasticity and neuronal maturation. The mitochondrion also...

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Literature Corpus work: 81249b53-c4b8-570d-975d-320ecc684f3b
DOI: 10.21203/rs.3.rs-158378/v1

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