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Polysaccharides from the fungus <i>Inonotus obliquus</i> activate macrophages into a tumoricidal phenotype via interaction with TLR2, TLR4 and Dectin-1a

2020-11-11

Abstract excerpt

<h4>Background</h4> Tumor-associated macrophages (TAMs) may both promote and suppress tumor development. Therefore, molecules that are able to activate and repolarize these cells into a tumoricidal phenotype could be of great interest as a new strategy for cancer immunotherapy. Fungal β-glucans have been suggested as a promising way of activating TAMs, but most of the research has been carried out on particulate...

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Literature Corpus work
811dfb95-ba32-5500-afcf-2cdea3b46fc9
DOI
10.1101/2020.11.11.378356
Open publication

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Polysaccharides from the fungus <i>Inonotus obliquus</i> activate macrophages into a tumoricidal phenotype via interaction with TLR2, TLR4 and Dectin-1aDOI 10.1101/2020.11.11.378356
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