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Immunostimulatory and anti-tumor activity of a water-soluble polysaccharide from Phellinus baumii mycelia

2011-05-01

Abstract excerpt

A 17-kDa water-soluble polysaccharide (PB) was isolated and purified from Phellinus baumii using the DEAE-Sephadex A-50 and LPLC-Sephadex G-75 methods. Exposure of RAW264.7 macrophages to PB resulted in a significant increase of the cellular proliferation rate, nitric oxide production and expression levels of the IL-1β, IL-18, IL-6, IL-12p35 and IL-12p40 genes. An MTT assay indicated that PB markedly suppressed th...

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Literature Corpus work
4054b9de-2743-5adc-8365-edb15f211693
DOI
10.1007/s11274-010-0545-x
Open publication

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