Article

Physiopathological changes of ferritin mRNA density and distribution in hippocampal astrocytes in the mouse brain

2022-04-01

Abstract excerpt

Astrocytes are thought to play a crucial role in brain iron homeostasis. How they accomplish this regulation in vivo remains unclear. In a recent transcriptomic analysis, we showed that polysomal Ftl1 and Fth1 mRNAs, encoding the ferritin light (Ftl) and heavy (Fth) chains that assemble into ferritin, a critical complex for iron storage and reduction, are enriched in perisynaptic astrocytic processes as compared...

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Literature Corpus work: 810b8575-cf90-57f2-b477-55483ec578e3
DOI: 10.1101/2022.04.01.486678

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