Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unveiling the impact of ferroptosis on diabetes‐associated cognitive decline through comprehensive single‐cell RNA sequencing and experimental studies

20 Apr 2025

Abstract excerpt

Diabetes-associated cognitive decline (DACD) is defined as an impairment of cognitive functions, including memory, attention and executive functions, attributed to chronic hyperglycemia and metabolic dysregulation associated with type 2 diabetes mellitus (T2DM). Ferroptosis is a regulated form of cell death that is dependent on iron and is primarily characterized by the excessive accumulation of lipid peroxides...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Ferroptosis and cancer prognosis
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40254912
DOI: 10.1111/febs.70101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unveiling the impact of ferroptosis on diabetes‐associated cognitive decline through comprehensive single‐cell RNA sequencing and experimental studiesPMID 40254912Read ↗

Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s DiseaseSemantic proximity Read ↗

FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer’s Disease: Evidence from Single-Cell Transcriptomic AnalysisSemantic proximity Read ↗

SLC40A1 mediates ferroptosis and cognitive dysfunction in type 1 diabetesSemantic proximity Read ↗

Mechanisms of Ferroptosis and Emerging Links to the Pathology of Neurodegenerative DiseasesSemantic proximity Read ↗

The Potential of Ferroptosis-Targeting Therapies for Alzheimer’s Disease: From Mechanism to Transcriptomic AnalysisSemantic proximity Read ↗

NOX4-mediated astrocyte ferroptosis in Alzheimer’s diseaseSemantic proximity Read ↗

Ferroptosis and iron metabolism in diabetes: Pathogenesis, associated complications, and therapeutic implicationsSemantic proximity Read ↗

A Bioinformatics Perspective on the Dysregulation of Ferroptosis and Ferroptosis-related Immune Cell Infiltration in Alzheimer's DiseaseSemantic proximity Read ↗

Uncovering the molecular networks of ferroptosis in the pathogenesis of type 2 diabetes and its complications: a multi-omics investigation.Semantic proximity Read ↗

Targeted RNAseq Revealed the Gene Expression Signature of Ferroptosis-Related Processes Associated with Disease Severity in Patients with Multiple SclerosisSemantic proximity Read ↗

Insights into targeted ferroptosis in mechanisms, biology, and role of Alzheimer's disease: an updateSemantic proximity Read ↗

Single-cell transcriptomics analysis of cellular heterogeneity and immune mechanisms in neurodegenerative diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.