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Centenarian hippocampus displays high levels of astrocytic metallothioneins

20 May 2024

Abstract excerpt

The hippocampus is a brain area linked to cognition. The mechanisms that maintain cognitive activity in humans are poorly understood. Centenarians display extreme longevity which is generally accompanied by better quality of life, lower cognitive impairment, and reduced incidence of pathologies including neurodegenerative diseases. We performed transcriptomic studies in hippocampus samples from individuals of...

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PMID: 38769809
DOI: 10.1111/acel.14201

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