Article

Developmental Acquisition of p53 Functions

2021-10-18

Abstract excerpt

Abstract: Remarkably, the p53 transcription factor, referred to as “the guardian of the genome”, is not essential for mammalian development. Moreover, efforts to identify p53‑dependent developmental events have produced contradictory conclusions. Given the importance of pluripotent stem cells as models of mammalian development, and their applications in regenerative medicine and disease, resolving thes...

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Literature Corpus work: 80f43d7c-f731-5350-a4b6-915a6e50a87b
DOI: 10.20944/preprints202110.0251.v1

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