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Senescence and Apoptosis: Architects of Mammalian Development

18 Jan 2021

Abstract excerpt

Mammalian development involves an exquisite choreography of cell division, differentiation, locomotion, programmed cell death, and senescence that directs the transformation of a single cell zygote to a mature organism containing on the order of 40 trillion cells in humans. How a single totipotent zygote undergoes the rapid stages of embryonic development to form over 200 different cell types is complex in the...

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PMID: 33537310
DOI: 10.3389/fcell.2020.620089

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