Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General Anesthesia

27 Apr 2022

Abstract excerpt

It has been widely demonstrated by numerous preclinical studies and clinical trials that the neonates receiving repeated or long-time general anesthesia (GA) could develop prolonged cognitive dysfunction. However, the definite mechanism remains largely unknown. Epigenetics, which is defined as heritable alterations in gene expression that are not a result of alteration of DNA sequence, includes DNA methylation,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anesthesia and Neurotoxicity Research
Share to ATP Synthase and ATPases Research
Share to Neonatal Respiratory Health Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35571375
DOI: 10.3389/fnmol.2022.877263

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General AnesthesiaPMID 35571375Read ↗

Neonatal anesthesia and dysregulation of the epigenomeSemantic proximity Read ↗

Emerging Role of Long Noncoding RNAs in Perioperative Neurocognitive Disorders and Anesthetic-Induced Developmental NeurotoxicitySemantic proximity Read ↗

Clinical Implications of Epigenetic Dysregulation in Perinatal Hypoxic-Ischemic Brain DamageSemantic proximity Read ↗

Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevofluraneSemantic proximity Read ↗

Characterization of DNA hydroxymethylation in hypothalamus of elderly mice with postoperative cognitive dysfunctionSemantic proximity Read ↗

[Epigenetics and epigenome. A step forward in the etiology and potential treatment of neurological diseases].Semantic proximity Read ↗

Epigenetic Manipulation of Brain-derived Neurotrophic Factor Improves Memory Deficiency Induced by Neonatal Anesthesia in RatsSemantic proximity Read ↗

Genetic and epigenetic insights into perioperative neurocognitive disorders: a narrative review.Semantic proximity Read ↗

Epigenetics modifiers: potential hub for understanding and treating neurodevelopmental disorders from hypoxic injurySemantic proximity Read ↗

Epigenetics in the nervous system.Semantic proximity Read ↗

Novel etiological and therapeutic strategies for neurodiseases: epigenetic understanding of gene-environment interactions.Semantic proximity Read ↗

Intergenerational Perioperative Neurocognitive DisorderSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.