Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic Mechanisms of Postoperative Cognitive Impairment Induced by Anesthesia and Neuroinflammation

21 Sept 2022

Abstract excerpt

Cognitive impairment after surgery is a common problem, affects mainly the elderly, and can be divided into postoperative delirium and postoperative cognitive dysfunction. Both phenomena are accompanied by neuroinflammation; however, the precise molecular mechanisms underlying cognitive impairment after anesthesia are not yet fully understood. Anesthesiological drugs can have a longer-term influence on protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anesthesia and Neurotoxicity Research
Share to Intensive Care Unit Cognitive Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36230916
DOI: 10.3390/cells11192954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic Mechanisms of Postoperative Cognitive Impairment Induced by Anesthesia and NeuroinflammationPMID 36230916Read ↗

DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative deliriumSemantic proximity Read ↗

Inflammatory signalling in postoperative cognitive dysfunctionsSemantic proximity Read ↗

Whole‐transcriptome sequencing identifies neuroinflammation, metabolism and blood–brain barrier related processes in the hippocampus of aged mice during perioperative periodSemantic proximity Read ↗

Epigenetics of Delirium and Aging: Potential Role of DNA Methylation Change on Cytokine Genes in Glia and Blood Along With AgingSemantic proximity Read ↗

Epigenetics of post-operative delirium: A genome-wide DNA methylation study of neurosurgery patientsSemantic proximity Read ↗

The genome‐wide DNA methylation profiles among neurosurgery patients with and without post‐operative deliriumSemantic proximity Read ↗

Association between the apolipoprotein E4 and postoperative cognitive dysfunction in elderly patients undergoing intravenous anesthesia and inhalation anesthesia.Semantic proximity Read ↗

Characterization of DNA hydroxymethylation in hypothalamus of elderly mice with postoperative cognitive dysfunctionSemantic proximity Read ↗

Glial Contribution to the Pathogenesis of Post-Operative Delirium Revealed by Multi-omic Analysis of Brain Tissue from Neurosurgery PatientsSemantic proximity Read ↗

Gene-Specific DNA Methylation Linked to Postoperative Cognitive Dysfunction in Apolipoprotein E3 and E4 MiceSemantic proximity Read ↗

The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General AnesthesiaSemantic proximity Read ↗

Transcriptome Profile in Hippocampus During Acute Inflammatory Response to Surgery: Toward Early Stage of PNDSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.