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Pilot study: Trehalose-induced remodelling of the human microbiota affects <i>Clostridioides difficile</i> infection outcome in an <i>in vitro</i> colonic model

2021-02-16

Abstract excerpt

Within the human intestinal tract, dietary, microbial- and host-derived compounds are used as signals by many pathogenic organisms, including Clostridioides difficile . Trehalose has been reported to enhance virulence of certain C. difficile ribotypes; however, such variants are widespread and not correlated with clinical outcomes for patients suffering from C. difficile infection (CDI). Here, we make prelimina...

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Literature Corpus work
808436ef-c9ec-5153-9d50-a10ed6208277
DOI
10.1101/2021.02.16.431513
Open publication

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Pilot study: Trehalose-induced remodelling of the human microbiota affects <i>Clostridioides difficile</i> infection outcome in an <i>in vitro</i> colonic modelDOI 10.1101/2021.02.16.431513
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