Article

High-cell-density production of adeno-associated viral vector serotype 6 by triple transfection in suspension HEK293 cell cultures

2023-02-02

Abstract excerpt

The use of adeno-associated viruses (AAV) as vectors for gene and cell therapy has risen considerably in recent years. Consequently, the amount of AAV vectors required during the validation and clinical trials has also increased. AAV serotype 6 (AAV6) is well-documented for its efficiency in transducing different cell types and has been successfully used in gene and cell therapy protocols. However, the number of v...

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Literature Corpus work: 806a7942-d43c-504f-8d9d-7f61c5081fce
DOI: 10.22541/au.167535214.41739207/v1

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