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Production of adeno‐associated viral vector serotype 6 by triple transfection of suspension HEK293 cells at higher cell densities

20 Jun 2023

Abstract excerpt

Abstract In recent years, the use of adeno‐associated viruses (AAVs) as vectors for gene and cell therapy has increased, leading to a rise in the amount of AAV vectors required during pre‐clinical and clinical trials. AAV serotype 6 (AAV6) has been found to be efficient in transducing different cell types and has been successfully used in gene and cell therapy protocols. However, the number of vectors required to...

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PMID: 37337925
DOI: 10.1002/biot.202300051

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