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Unravelling the essential elements for recombinant adeno-associated virus (rAAV) production in animal cell-based platforms

29 Apr 2024

Abstract excerpt

Recombinant adeno-associated viruses (rAAVs) stand at the forefront of gene therapy applications, holding immense significance for their safe and efficient gene delivery capabilities. The constantly increasing and unmet demand for rAAVs underscores the need for a more comprehensive understanding of AAV biology and its impact on rAAV production. In this literature review, we delved into AAV biology and rAAV...

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PMID: 38692443
DOI: 10.1016/j.biotechadv.2024.108370

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