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Article

Absence of the CXCR4 Antagonist EPI-X4 from Pharmaceutical Human Serum Albumin Preparations

2021-03-11

Abstract excerpt

<h4>Background: </h4> Endogenous Peptide Inhibitor of CXCR4 (EPI-X4) is a natural antagonist of the CXC chemokine receptor 4 (CXCR4). EPI-X4 is a 16-mer peptide that is released from human serum albumin (HSA) by acidic aspartic proteases such as Cathepsin D and E. Since human serum albumin (HSA) is an important medicinal substance we asked whether different pharmaceutical HSA products contain EPI-X4 which could ha...

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Identifiers and source

Literature Corpus work
802aafc9-1524-54a8-bbd2-433c46d2f002
DOI
10.20944/preprints202103.0309.v1
Open publication

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Absence of the CXCR4 Antagonist EPI-X4 from Pharmaceutical Human Serum Albumin PreparationsDOI 10.20944/preprints202103.0309.v1
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