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Article

Elucidation of Inflammatory-Fibrotic Microenvironment in Human Urethral Stricture Disease

2026-05-04

Abstract excerpt

<title>Abstract</title> <p>(248 words) Background: Urethral stricture disease (USD) is marked by inflammation with subsequent tissue fibrosis that disrupts urinary flow. Recent studies suggest lower urinary tract biome dysbiosis increases proinflammatory cytokines, impeding tissue repair as well as promoting fibrotic scarring of the urethra. Despite these insights, the comprehensive molecular mechanisms underlyin...

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Literature Corpus work
09407888-76dc-503d-b9bb-92377ac48ec5
DOI
10.21203/rs.3.rs-9307477/v1
Open publication

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