Article

Commitment to cytokinetic furrowing requires the coordinate activity of microtubules and Plk1

2024-09-16

Abstract excerpt

<h4>Summary</h4> At anaphase, spindle microtubules (MTs) position the cleavage furrow and trigger actomyosin assembly by localizing the small GTPase RhoA and the scaffolding protein anillin to a narrow band along the equatorial cortex [1–6]. Using vertebrate somatic cells we examined the temporal control of furrow assembly. Although its positioning commences at anaphase onset, furrow maturation is not complete un...

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Literature Corpus work: 7ffea5a2-648d-5502-a5e4-fc98e0bb4d1e
DOI: 10.1101/2024.09.16.612913

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