Article
Two phases of astral microtubule activity during cytokinesis in C. elegans embryos.
Developmental cell - 1 Apr 2006
Motegi Fumio, Velarde Nathalie V, Piano Fabio, Sugimoto Asako
Abstract excerpt
Microtubules of the mitotic spindle are believed to provide positional cues for the assembly of the actin-based contractile ring and the formation of the subsequent cleavage furrow during cytokinesis. In Caenorhabditis elegans, astral microtubules have been thought to inhibit cortical contraction outside the cleavage furrow. Here, we demonstrate by live imaging and RNA interference (RNAi) that astral microtubules...
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