Article

The dynamic alternation of monocytes phenotypes and gene signature-related biomarkers in the airways and blood reveals myeloid subset-driven inflammation and lung fibrosis in hypercapnia following pulmonary sepsis- associated ARDS

2024-03-28

Abstract excerpt

<h4>Background: </h4> ARDS, a severe complication of sepsis, often exhibits hypercapnia, whose immunological mechanisms remain elusive. Our study aimed to investigate the pathogenesis of hypercapnia in pulmonary sepsis-associated ARDS and identify potential therapeutic targets. Methods Between December 2022 and April 2023, we conducted a single-center, prospective study with sixty-one severe pneumonia patients. E...

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Literature Corpus work: 7ff52826-6dfa-5988-ad19-2f010c12e545
DOI: 10.21203/rs.3.rs-4145872/v1

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