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<i>CTNNB1</i> ( <i>β</i> -catenin) mutations in NSCLC: clinicogenomic characteristics, prognostic value and implications for therapy

2025-11-14

Abstract excerpt

Although mutations in CTNNB1 have long been associated with cancer, their impact in patients with non-small cell lung cancer (NSCLC) is not well understood. Beyond a potential role in the acquired resistance setting of EGFR -mutant NSCLC, little is known about the clinical and molecular characteristics of NSCLC patients harboring these mutations. Here, we identify 302/15,688 (1.9%) NSCLC patients with CTNNB1 mu...

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Literature Corpus work
7fde0df1-96fa-5069-8d6e-c6d842755c37
DOI
10.1101/2025.11.12.25338824
Open publication

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<i>CTNNB1</i> ( <i>β</i> -catenin) mutations in NSCLC: clinicogenomic characteristics, prognostic value and implications for therapyDOI 10.1101/2025.11.12.25338824
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