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Article

CTNNB1 Mutations in Non-small Cell Lung Cancer: Clinicopathological Characteristics of a Small Cohort.

Anticancer research - 1 Jul 2026

Improta Giuseppina, Vita Giulia, Tartarone Alfredo, Calice Giovanni, Omer Ludmila Carmen, Domenica Ferrara, Zupa Angela

Abstract excerpt

BACKGROUND/AIM: Mutations in β-catenin gene (CTNNB1) are very rare in non-small cell lung cancer (NSCLC) and frequently coexist with epidermal growth factor receptor (EGFR) mutations. This study evaluated the clinicopathological characteristics and treatments outcomes of 14 patients harboring CTNNB1 mutations. PATIENTS AND METHODS: A total of 266 NSCLC samples underwent Next Generation Sequencing (NGS) from...

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Identifiers

PMID: 42373286
DOI: 10.21873/anticanres.18234

Genes

CTNNB1
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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