Article

Harnessing AI to Reveal CTNNB1’s Central Role in Breast Cancer Progression and Drug Discovery

2025-09-30

Abstract excerpt

CTNNB1 encodes β-catenin, a multifunctional protein critically involved in cell adhesion and canonical Wnt signaling, fundamental for cellular homeostasis, gene regulation, and proliferation. In breast cancer, aberrant activation of the Wnt/β-catenin pathway is commonly observed, particularly in aggressive subtypes such as triple-negative breast cancer (TNBC), where elevated β-catenin correlates with high tumor gr...

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Literature Corpus work: 99797316-3168-5412-a32b-bb3fc89a416d
DOI: 10.20944/preprints202509.2524.v1

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