Article

Distinct mutational profile of Lynch syndrome colorectal cancers diagnosed under regular colonoscopy surveillance

2020-08-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Regular colonoscopy even with short intervals does not prevent all colorectal cancers (CRC) in Lynch syndrome (LS). In the present study, we asked whether cancers detected under regular colonoscopy surveillance (incident cancers) are phenotypically different from cancers detected at first colonoscopy (prevalent cancers). <h4>Methods</h4> We analyzed clinical, histological, imm...

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Literature Corpus work: 7fc7d547-8717-51a5-be0a-e8433d72a5e5
DOI: 10.1101/2020.08.21.20179127

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