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Original research: Impact of surveillance colonoscopy on colorectal cancer incidence and mortality in Lynch syndrome - a national observational cohort study of patients in the English NHS 2010-2022

2026-04-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Lynch syndrome (LS) is a cancer susceptibility syndrome caused by germline pathogenic variants in DNA mismatch repair (MMR) genes. Due to increased risk of colorectal cancer (CRC), enhanced colonoscopic surveillance is recommended for heterozygote MMR-carriers. <h4>Objective</h4> Using a registry of English LS patients linked to digital National Health Service records, we a...

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Literature Corpus work: 036eff95-cb3f-5578-901f-cf3b5423ec31
DOI: 10.64898/2026.04.16.26351020

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