Article

An efficient gene targeting system using Δ <i>ku80</i> and functional analysis of Cyp51A in <i>Trichophyton rubrum</i>

2024-04-19

Abstract excerpt

Trichophyton rubrum is one of the most frequently isolated fungi in patients with dermatophytosis. Despite its clinical significance, the molecular mechanisms of drug resistance and pathogenicity of T. rubrum remain to be elucidated because of the lack of genetic tools, such as efficient gene targeting systems. In this study, we generated a T. rubrum strain that lacks the nonhomologous end-joining-related gene...

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Literature Corpus work: 7f97775b-8c26-5fcc-a3d2-5a155946f833
DOI: 10.1101/2024.04.18.590175

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