Article

The Ptk2-Pma1 pathway enhances tolerance to terbinafine in <i>Trichophyton rubrum</i>

2023-12-08

Abstract excerpt

The increasing prevalence of dermatophyte resistance to terbinafine, a key drug in the treatment of dermatophytosis, represents a significant obstacle to treatment. Trichophyton rubrum is the most commonly isolated fungus in dermatophytosis. In T. rubrum , we identified TERG_07844, a gene encoding a previously uncharacterized putative protein kinase, as an ortholog of budding yeast Saccharomyces cerevisiae poly...

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Literature Corpus work: 669b9cd1-9d08-567b-b1a4-ff70f83dd6f9
DOI: 10.1101/2023.12.07.570643

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