Article

Deep mining of early antibody response in COVID-19 patients yields potent neutralisers and reveals high level of convergence

2020-12-29

Abstract excerpt

Passive immunisation using monoclonal antibodies will play a vital role in the fight against COVID-19. Until now, the majority of anti-SARS-CoV-2 antibody discovery efforts have relied on screening B cells of patients in the convalescent phase. Here, we describe deep-mining of the antibody repertoires of hospitalised COVID-19 patients using a combination of phage display technology and B cell receptor (BCR) repert...

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Literature Corpus work: 7f686477-6635-56cd-bed2-4c1267330ed6
DOI: 10.1101/2020.12.29.424711

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