Article

Profiling B cell immune responses to identify neutralizing antibodies from convalescent COVID-19 patients

2020-08-12

Abstract excerpt

The pandemic Coronavirus Disease 2019 (COVID-19) causes noticeable morbidity and mortality worldwide. In addition to vaccine and antiviral drug therapy, the use of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) neutralizing antibodies for treatment purposes is a viable alternative. In this study, we aimed to profile the humoral responses and identify neutralizing antibodies against SARS-CoV-2 using h...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 93f2f03a-1a1a-509d-b602-d01c34c1773a
DOI: 10.21203/rs.3.rs-38173/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Profiling B cell immune responses to identify neutralizing antibodies from convalescent COVID-19 patientsDOI 10.21203/rs.3.rs-38173/v2Read

Elucidating the Humoral Immune Response to SARS-CoV-2: Isolation and Characterization of Monoclonal Antibodies from Convalescent COVID-19 PatientsSemantic proximity Read

Neutralizing antibodies targeting SARS-CoV-2 spike proteinSemantic proximity Read

Cross-neutralization antibodies against SARS-CoV-2 and RBD mutations from convalescent patient antibody librariesSemantic proximity Read

Preclinical Efficacy of IMM-BCP-01, a Highly Active Patient-Derived Anti-SARS-CoV-2 Antibody CocktailSemantic proximity Read

A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike proteinSemantic proximity Read

Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B CellsSemantic proximity Read

High seroreactivity against SARS-CoV-2 Spike epitopes in a pre SARS-CoV-2 cohort: implications for antibody testing and vaccine designSemantic proximity Read

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2Semantic proximity Read

Multi-Clonal Live SARS-CoV-2 In Vitro Neutralization by Antibodies Isolated from Severe COVID-19 Convalescent DonorsSemantic proximity Read

Epitope Analysis of Anti-SARS-CoV-2 Neutralizing Antibodies.Semantic proximity Read

Characterization of neutralizing antibodies from a SARS-CoV-2 infected individualSemantic proximity Read

Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralizationSemantic proximity Read