Article

In vivo assessment of non-dopaminergic systems in Parkinson's disease with Positron Emission Tomography

2011-01-01

Abstract excerpt

Parkinson's disease (PD) is characterized by a progressive loss of nigrostriatal dopaminergic neurons. Non-dopaminergic neurotransmission is also impaired. Intraneuronal Lewy bodies, the pathological hallmark of PD, have been observed in serotoninergic, noradrenergic, and cholinergic neurons. Dysfunction of these systems could play a role in the occurrence of non-motor symptoms including fatigue. However, the exte...

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Literature Corpus work: 7f238113-cdbd-54eb-a97b-1d06ddf6dba5
DOI: 10.25560/6916

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