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Interaction between gene polymorphisms in MLL3 gene and TGF-β signal pathway with the susceptibility of type B aortic dissection in the Chinese population

2022-01-13

Abstract excerpt

<h4>Objective: </h4> To investigate the impact of MLL3 polymorphisms and Transforming growth factor-β (TGF-β) pathway additional their interactions with type B aortic dissection (AD) risk based on the Chinese population. Methods: We investigated the MLL3 (rs10244604, rs6963460, rs1137721), TGFβ1 (rs1800469), TGFβ2 (rs900), TGFR1 (rs1626340) and TGFR2 (rs4522809) gene polymorphisms analysis. Logistic regression wa...

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Literature Corpus work
7f1e0ed4-5a78-53d7-9d26-083160582ac8
DOI
10.21203/rs.3.rs-1215325/v1
Open publication

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