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Article

Association of gene polymorphisms in MYH11 and TGF-β signaling with the susceptibility and clinical outcomes of DeBakey type III aortic dissection.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2022

Chang Yafei, Yuan Qinghua, Jiang Peipei, Sun Ling, Ma Yitong, Ma Xiang

Abstract excerpt

To investigate the association of myosin heavy chain protein 11 (MYH11) and transforming growth factor β signaling-related gene polymorphisms with the susceptibility of DeBakey type III aortic dissection (AD) and its clinical outcomes. Four single-nucleotide polymorphism (SNPs) (MYH11 rs115364997, rs117593370, TGFB1 rs1800469, and TGFBR1 rs1626340) were analyzed in patients with DeBakey III AD (173) and healthy...

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Share to Aortic Dissection
Share to Genetic Predisposition to Disease
Share to Genotype
Share to Myosin Heavy Chains
Share to Polymorphism, Single Nucleotide
Share to Receptor, Transforming Growth Factor-beta Type I
Share to Transforming Growth Factor beta
Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 34729648
DOI: 10.1007/s00335-021-09929-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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