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Article

Association of gene polymorphisms in FBN1 and TGF-β signaling with the susceptibility and prognostic outcomes of Stanford type B aortic dissection.

BMC medical genomics - 20 Mar 2022

Sun Ling, Chang Yafei, Jiang Peipei, Ma Yitong, Yuan Qinghua, Ma Xiang

Abstract excerpt

BACKGROUND: This study is aimed at investigating the association of Fibrillin-1 (FBN1) and transforming growth factor β (TGF-β) signaling-related gene polymorphisms with the susceptibility of Stanford type B aortic dissection (AD) and its clinical prognostic outcomes. METHODS: Five single-nucleotide polymorphism (SNPs) (FBN1rs 145233125, rs201170905, rs11070646, TGFB1rs1800469, and TGFB2rs900) were analyzed in...

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Identifiers

PMID: 35307021
DOI: 10.1186/s12920-022-01213-z
PMCID: PMC8935688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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